| Popis: |
Unique characteristics discriminate germ cell tumors (GCTs) from other solid malignancies. Patients are predominantly young men between 15 and 40 years with few comorbidities (if any); tumors are particularly sensitive to platinum-based chemotherapy; and a cure is still possible with salvage approaches in patients with progression after first-line chemotherapy. Curative salvage strategies involve conventional-dose chemotherapy (CDCT) or, alternatively, high-dose chemotherapy with autologous stem cell transplantation (HDCT/ASCT), which—in contrast to virtually all other types of solid tumors—can be highly effective.1, 2, 3, 4, 5, 6, 7, 8, 9, 10 |
