Quality of life in relation to constipation among opioid users
| Autor: | Yves F. D. M. Prevoo, Donald L. van der Peet, Ron M. C. Herings, Rogier M. Klok, Fernie J. A. Penning-van Beest, Pieter van den Haak |
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| Přispěvatelé: | Surgery, Epidemiology and Data Science |
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Constipation Psychometrics Databases Factual medicine.medical_treatment Laxative Pain Pharmacy Disease Statistics Nonparametric Quality of life Surveys and Questionnaires Adaptation Psychological medicine Health Status Indicators Humans In patient business.industry Health Policy Middle Aged Analgesics Opioid Opioid Physical therapy Disease Progression Quality of Life Female medicine.symptom business Stress Psychological medicine.drug |
| Zdroj: | Penning-Van Beest, F J A, Van Den Haak, P, Klok, R M, Prevoo, Y F D M, Van Der Peet, D L & Herings, R M C 2010, ' Quality of life in relation to constipation among opioid users ', Journal of Medical Economics, vol. 13, no. 1, pp. 129-135 . https://doi.org/10.3111/13696990903584436 Journal of Medical Economics, 13(1), 129-135. Taylor and Francis Ltd. |
| ISSN: | 1941-837X 1369-6998 |
| Popis: | Objective: Opioid users often experience constipation. In this study the impact of constipation on QoL was assessed in patients using opioids either for non-advanced illness or advanced illness. Methods: Patients using opioids, recruited via public pharmacies, were asked to complete questionnaires on opioid use, constipation and the EuroQol five-dimension questionnaire (EQ-5D). Patients with a severe non-curable disease and relatively short life-expectancy were classified as having an advanced illness; a disabling yet not directly life-threatening condition was defined as non-advanced illness. Constipation was assessed based on questions on opioid side-effects and laxative use. EQ-5D index scores were compared between patients with and without constipation using Wilcoxon two-samples test. Results: Questionnaires were returned by 588 patients with non-advanced illness, of whom 326 (55%) were classified as having constipation and by 113 patients with advanced illness, of whom 76 (67%) were classified as having constipation. The median EQ-5D index, a weighted health state index score with 1 = full health, was lower in patients with constipation than in patients without constipation (0.31 vs. 0.65, p |
| Databáze: | OpenAIRE |
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