A Rare Cause of Abdominal Pain and Mass in an 18-Year-Old Patient: A Diagnostic Dilemma
| Autor: | Masooma Niazi, Ariyo Ihimoyan, Anil Dev, Muhammad Umar Kamal, Vamshidhar Vootla, Mohamed ElZaeedi, Sridhar Chilimuri, Hassan Tariq, Brian F Gilchrist |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Endoscopic ultrasound
medicine.medical_specialty Abdominal pain Exploratory laparotomy medicine.medical_treatment Gastric carcinoids Case Report Zollinger-Ellison syndrome Gastroenterology 03 medical and health sciences 0302 clinical medicine Neuroendocrine tumor Internal medicine Medicine Gastrin Gastrinoma medicine.diagnostic_test business.industry Stomach Primary peripancreatic gastrinoma medicine.disease Curvatures of the stomach digestive system diseases medicine.anatomical_structure 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Gastroenterology Research |
| ISSN: | 1918-2813 1918-2805 |
| Popis: | We present a case of an 18-year-old male who presented with complains of abdominal pain, nausea and vomiting for 2 years. An esophagogastroduodenoscopy (EGD) revealed a 3 mm nodule on the lesser curvature of the stomach and prominent gastric folds. Biopsy of the nodule revealed a well-differentiated neuroendocrine tumor (NET) in lamina prop with focal extension into muscularis mucosa consistent with a gastric carcinoid. Tumor cells stained with neuron-specific enolase (NSE), chromogranin and synaptophysin only. The prominent gastric fold biopsy revealed gastric fundic mucosa with mucosal edema and focal mild chronic inflammation. Serum gastrin level was found to be 2,083 pg/mL. Abdomen CT and endoscopic ultrasound (EUS) revealed a mass near the pancreatic neck. These findings were consistent with a functional gastrin producing well-differentiated grade 1 neuroendocrine neoplasm (gastrinoma). The patient underwent exploratory laparotomy with resection of the mass and resulting in normalization of gastrin levels. |
| Databáze: | OpenAIRE |
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