Serological characterization of murine monoclonal antibodies directed against acquired B red cells
| Autor: | F. Guignier, M. Reviron, S. Veaux, D. Janvier, M. Benbunan |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Erythrocytes
Hemagglutination medicine.drug_class Carbohydrates Neuraminidase Biology Cross Reactions Monoclonal antibody Epitope Serology ABO Blood-Group System Mice Antigen ABO blood group system medicine Animals Humans Mice Inbred BALB C Antibodies Monoclonal Acetylation Hematology General Medicine Virology Molecular biology Red blood cell medicine.anatomical_structure Blood Grouping and Crossmatching biology.protein Antibody Trisaccharides |
| Zdroj: | Vox sanguinis. 59(2) |
| ISSN: | 0042-9007 |
| Popis: | Balb/c mice were immunized with acquired B red cells. Twelve clones specific for acquired B red cells were obtained from two fusions. A detailed investigation of three clones is reported here. These antibodies appear to be directed to the B-like epitope since they are inhibited by galactosamine and fail to react after acetylation of red cells. E 231 is an example of a series of antibodies closely specific for acquired B red cells which can be useful in elucidating some AB0 typing problems. E 167 and F 47 showed a cross-reactivity with A1 red cells and a synthetic A trisaccharide. No affinity for B antigen could be demonstrated for any of the antibodies. |
| Databáze: | OpenAIRE |
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