Alveolar bone regeneration for immediate implant placement using an injectable bone substitute: an experimental study in dogs
Autor: | Olivier Gauthier, Jérôme Guicheux, Damien Boix, Paul Pilet, Guy Daculsi, Pierre Weiss, Gael Grimandi |
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Přispěvatelé: | Matériaux d'intérêt biologique, Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de chirurgie, Ecole Nationale Vétérinaire de Nantes, Centre de microscopie électronique, Université de Nantes (UN), Weiss, Pierre |
Jazyk: | angličtina |
Rok vydání: | 2004 |
Předmět: |
MESH: Dental Implantation
Endosseous Ceramics Bone density Dentistry Biocompatible Materials 02 engineering and technology Beagle MESH: Dogs MESH: Bone Regeneration Hypromellose Derivatives 0302 clinical medicine MESH: Methylcellulose MESH: Biocompatible Materials Bone Density Osteogenesis MESH: Animals Tooth Socket MESH: Dental Implants MESH: Osteogenesis MESH: Bone Density Bone substitutes MESH: Alveolar Process MESH: Tooth Socket Dental Implantation Endosseous General Engineering 021001 nanoscience & nanotechnology MESH: Calcium Phosphates Bone regeneration medicine.anatomical_structure Periodontics Female 0210 nano-technology MESH: Bone Substitutes Methylcellulose Article Osseointegration Injections 03 medical and health sciences Dogs MESH: Ceramics stomatognathic system Alveolar Process medicine Animals MESH: Injections [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials Dental alveolus Wound Healing business.industry Alveolar process Dental implants MESH: Osseointegration 030206 dentistry [SDV.IB.BIO] Life Sciences [q-bio]/Bioengineering/Biomaterials MESH: Wound Healing Durapatite Calcium phosphates Implant MESH: Durapatite business Wound healing MESH: Female |
Zdroj: | Journal of periodontology Journal of periodontology, American Academy of Periodontology, 2004, 75 (5), pp.663-71 Scopus-Elsevier |
ISSN: | 0022-3492 |
Popis: | International audience; BACKGROUND: The aim of the present study was to assess the efficacy of a ready-to-use injectable bone substitute for bone regeneration around dental implants placed into fresh extraction sockets. METHODS: Third and fourth mandibular premolars were extracted from three beagle dogs and the interradicular septa were surgically reduced to induce a mesial bone defect. Thereafter, titanium implants were immediately placed. On the left side of the jaw, mesial bone defects were filled with an injectable bone substitute (IBS), obtained by combining a polymer and biphasic calcium phosphate ceramic granules. The right defects were left unfilled as controls. After 3 months of healing, specimens were prepared for histological and histomorphometric evaluations. RESULTS: No post-surgical complications were observed during the healing period. In all experimental conditions, histological observations revealed a lamellar bone formation in contact with the implant. Histomorphometric analysis showed that IBS triggers a significant (P |
Databáze: | OpenAIRE |
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