Results of a prospective cardiovascular disease prevention program
| Autor: | Arn H. Eliasson, Mariam Kashani, Marina Vernalis |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
BP
blood pressure RYP Rate-Your-Plate Stress management BMI body mass index in kg/m2 Epidemiology CIMT carotid intima-media thickness IPAQ International Physical Activity Questionnaire Tot Chol total cholesterol in mg/dL Disease TLC therapeutic lifestyle change LDL low density lipoprotein Trig triglycerides in mg/dL 0302 clinical medicine NDRI nicotine and dopamine reuptake inhibitor SPSS Statistical Package for the Social Science 030212 general & internal medicine Prospective cohort study Sys BP systolic blood pressure in mm Hg CHP Cardiovascular Health Program Therapeutic lifestyle change PSS Perceived Stress Scale TCA tricyclic antidepressant Regular Article Cardiovascular disease α Blocker alpha blocker ARB angiotensin receptor blocker Statin HMG-CoA reductase inhibitor Medicine DPP4 mdipeptidyl peptidase 4 inhibitor IRB institutional review board medicine.medical_specialty Waist PSQI Pittsburgh Sleep Quality Index HOMA-IR homeostatic model assessment for insulin resistance 030209 endocrinology & metabolism NP nurse practitioner Dias BP diastolic blood pressure in mm Hg ESS Epworth Sleepiness Scale ACEi angiotensin converting enzyme inhibitor 03 medical and health sciences Insulin resistance medicine SNRI serotonin-norepinephrine reuptake inhibitor Medical prescription CCB calcium channel blocker SSRI selective serotonin reuptake inhibitor CLIA Clinical Laboratory Improvement Amendments business.industry Prevention Public Health Environmental and Occupational Health SARI serotonin antagonist and reuptake inhibitor Anthropometry Cardiovascular risk medicine.disease WC waist circumference in cm Behavioral intervention β blocker beta blocker MACE major adverse cardiovascular events Physical therapy SD standard deviation business FBG fasting blood glucose in mg/dL Body mass index |
| Zdroj: | Preventive Medicine Reports, Vol 22, Iss, Pp 101344-(2021) Preventive Medicine Reports |
| ISSN: | 2211-3355 |
| Popis: | The Cardiovascular Health Program (CHP) Registry is a 12-month, prospective study of therapeutic lifestyle change (TLC). Adult participants received comprehensive assessment of health behaviors and cardiovascular disease (CVD) risk factors. Personalized TLC action plans addressed modifiable health behaviors for diet, exercise, stress management, and sleep. Participants attended a half-day interactive workshop and met face-to-face with certified health coaches four times over 6 months. Monthly telephonic coaching for 6 more months completed the intervention. Measured outcomes included adherence to behavioral prescriptions, anthropometrics, CVD-relevant laboratory tests, and for a subset of participants, carotid intima-media thickness (CIMT). Of 965 participants, 648 (67%) completed the program and were included in the analysis. Participants were of mean age 55.4 ± 12.5 years, 57% women, and racially diverse. Adherence to prescribed TLC was substantial: dietary behaviors at goal rose from 53% to 86%, exercise 44% to 66%, perceived stress 65% to 79%, and sleep quality 28% to 49%. For participants with abnormal anthropometrics at baseline, there were improvements in body mass index in 63%, waist circumference (men 71%, women 74%), systolic BP 69%, and diastolic BP 71%. For participants with abnormal laboratory values at baseline, there were improvements in total cholesterol in 74%, LDL-cholesterol 65%, triglycerides 86%, fasting glucose 72%, and insulin resistance 71%. Improvements were not driven by prescribed medications. CIMT improved or showed no change in 70% of those measured, associated with significant improvements in sleep quality and longer total sleep time. Longer trials incorporating controls and major adverse CVD events are warranted. |
| Databáze: | OpenAIRE |
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