Reversibility of pulmonary artery hypertension in aortic stenosis after aortic valve replacement
| Autor: | Michael S. Proctor, Gerald P. Tracy, Cathleen S. Hizny |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Aortic valve medicine.medical_specialty Systolic hypertension Hypertension Pulmonary Diastole Blood Pressure Pulmonary Artery Aortic valve replacement Internal medicine medicine.artery medicine Humans Aged Retrospective Studies business.industry Aortic Valve Stenosis Middle Aged medicine.disease Pulmonary hypertension Stenosis medicine.anatomical_structure Aortic Valve Heart Valve Prosthesis Aortic valve stenosis Pulmonary artery Cardiology Female Vascular Resistance Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Annals of Thoracic Surgery. 50:89-93 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/0003-4975(90)90095-n |
| Popis: | Fifty-two surgical patients with isolated aortic valve stenosis were studied preoperatively and postoperatively to determine the incidence of pulmonary hypertension and its response to surgical intervention. Pulmonary artery systolic hypertension was classified as absent (group 1, less than 30 mm Hg), mild (group 2, 30 to 39 mm Hg), moderate (group 3, 40 to 59 mm Hg), and severe (group 4, greater than 60 mm Hg). Thirty-seven of our patients (71%) had preoperative pulmonary hypertension. There was a positive correlation between left ventricular end-diastolic pressure and both systolic and diastolic pulmonary artery pressures preoperatively (p less than 0.001). After operation we found a decrease in mean systolic pulmonary pressure in group 4, from 85.8 +/- 23 mm Hg to 41.2 +/- 10.4 mm Hg (a 52% decrease, p less than 0.001), and in group 3, from 48.9 +/- 5.9 mm Hg to 32.1 +/- 7.1 mm Hg (a 34% decrease, p less than 0.001). A significant decrease in the mean diastolic pressure was found only in group 4, in which the pressure decreased from 33.7 +/- 8.7 mm Hg to 26.0 +/- 7.6 mm Hg (p less than 0.05). The operative mortality was 1.9%. Our data indicate that pulmonary artery hypertension in aortic stenosis is common, is related to end-diastolic pressure, and can be expected to improve in the early postoperative period. |
| Databáze: | OpenAIRE |
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