Bilateral visual projections exist in non-teleost bony fish and predate the emergence of tetrapods
| Autor: | Karine Duroure, Robin J. Vigouroux, Rodrigo Suárez, Juliette Vougny, Kim T. Nguyen-Ba-Charvet, Alain Chédotal, Eloisa Herrera, Shahad Albadri, Filippo Del Bene, Ingo Braasch, Peter Kozulin |
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| Přispěvatelé: | Agence Nationale de la Recherche (France), National Institutes of Health (US), Institut de la Vision, Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Génétique et Biologie du Développement, Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), University of Queensland [Brisbane], Michigan State University [East Lansing], Michigan State University System, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), HAL-SU, Gestionnaire, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Instituto de Neurociencias de Alicante |
| Rok vydání: | 2021 |
| Předmět: |
Fish Proteins
Retinal Ganglion Cells genetic structures [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology Visual system Eye ZIC2 Retinal ganglion Functional Laterality Retina Article [PHYS] Physics [physics] 03 medical and health sciences 0302 clinical medicine medicine Animals Humans Visual Pathways 14. Life underwater Zebrafish ComputingMilieux_MISCELLANEOUS 030304 developmental biology [PHYS]Physics [physics] Vision Binocular 0303 health sciences Multidisciplinary biology Fishes Brain Nuclear Proteins Cell Differentiation Anatomy biology.organism_classification Biological Evolution eye diseases Ganglion [SDV.BDD.EO]Life Sciences [q-bio]/Development Biology/Embryology and Organogenesis medicine.anatomical_structure Retinal ganglion cell Laterality sense organs Binocular vision 030217 neurology & neurosurgery Transcription Factors |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Science Science, American Association for the Advancement of Science, 2021, 372 (6538), pp.150-156. ⟨10.1126/science.abe7790⟩ Science, 2021, 372 (6538), pp.150-156. ⟨10.1126/science.abe7790⟩ |
| ISSN: | 1095-9203 0036-8075 |
| Popis: | In most vertebrates, camera-style eyes contain retinal ganglion cell neurons that project to visual centers on both sides of the brain. However, in fish, ganglion cells were thought to innervate only the contralateral side, suggesting that bilateral visual projections appeared in tetrapods. Here we show that bilateral visual projections exist in non-teleost fishes and that the appearance of ipsilateral projections does not correlate with terrestrial transition or predatory behavior. We also report that the developmental program that specifies visual system laterality differs between fishes and mammals, as the Zic2 transcription factor, which specifies ipsilateral retinal ganglion cells in tetrapods, appears to be absent from fish ganglion cells. However, overexpression of human ZIC2 induces ipsilateral visual projections in zebrafish. Therefore, the existence of bilateral visual projections likely preceded the emergence of binocular vision in tetrapods. This work was supported by Programme Investissements d’Avenir IHU FOReSIGHT (ANR-18-IAHU-01) (A.C. and F.D.B.), INSERM cross-cutting program HuDeCA 2018 (A.C.), NIH R01OD011116 (I.B.), and UQ Amplify Fellowship (R.S.) |
| Databáze: | OpenAIRE |
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