Additional file 1 of Efficacy and safety of dual intravenous artesunate plus quinine compared to intravenous artesunate for cerebral malaria in a triple blinded parallel multisite randomized controlled trial in Nigerian children: DUAL PAQ TRIAL Protocol

Autor: Alao, Michael Abel, Orimadegun, Adebola Emmanuel, Ibrahim, Olayinka Rasheed, Oyenuga, Abayomi O., Asinobi, Adanze Onyenonachi, Gbadero, Daniel Adedosu, Okoye, Ifeoma Joy, Nna, Emmanuel Okechukwu
Rok vydání: 2021
Předmět:
ISSN: 1465-1858
DOI: 10.6084/m9.figshare.16841087
Popis: Additional file 1: Table S1. The supplementary shows published data for the outcomes for interventions for cerebral malaria. Outcome for intravenous quinine alone was 23% to 26% while combines intravenous quinine and artesunate is 12.5%. Sinclair D, Donegan S, Isba R, Lalloo DG: Artesunate versus quinine for treating severe malaria. The Cochrane Library. 2012, 10.1002/14651858.CD005967.pub4.a Hien TT, Arnold K, Vinh H, et al Comparison of artemisinin suppositories with intravenous artesunate and intravenous quinine in the treatment of cerebral malaria. Trans R Soc Trop Med Hyg 1992; 86: 582–83.b Bartoloni A, Tomasoni L, Bartalesi F, Sani S, Zammarchi L, Castelli F, et al. Combined intravenous treatment with artesunate and quinine for severe malaria in Italy. Am J Trop Med Hyg 2010; 83: 274–76.c
Databáze: OpenAIRE