Creatine phosphokinase and psychosis
| Autor: | Daniel Schweid, Joel S. Steinberg, Howard S. Sudak |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Adult
Male Psychosis medicine.medical_specialty Arts and Humanities (miscellaneous) Internal medicine medicine Retrospective analysis Humans In patient Aspartate Aminotransferases Creatine Kinase Inpatient service Retrospective Studies Psychiatric Status Rating Scales biology business.industry fungi Retrospective cohort study Middle Aged medicine.disease Hospitalization Psychiatry and Mental health Psychotic Disorders Psychiatric status rating scales Acute Disease biology.protein Physical therapy Creatine kinase Serum creatine phosphokinase business |
| Zdroj: | Archives of general psychiatry. 26(3) |
| ISSN: | 0003-990X |
| Popis: | A retrospective analysis done on all available charts of each patient admitted to a psychiatric inpatient service during a one-year period provided 144 cases. Thirty-nine of these (27%) showed elevations of serum creatine phosphokinase (CPK) activity, but 16 of these 39 elevations (41% of total CPK elevations) occurred in patients who had received intramuscular injections and, consequently, were excluded from this study. Of the remaining 128 patients, 35 were diagnosed "psychotic" by mental status criteria. The dimension of "acuteness" of psychosis could not be precisely assessed, but 19 of the psychotic patients (54%) had elevations of serum CPK activity. Of the 93 patients determined to be "nonpsychotic" by mental status criteria, only four (4%) had CPK elevations. These elevations were unexplained. The probability of this distribution occurring on a chance basis is |
| Databáze: | OpenAIRE |
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