Risk factors for transfer from Respiratory Intermediate Care Unit to Intensive Care Unit in COVID-19
Autor: | Elena Capozza, Michela Dimitri, Valentina Di Lecce, Luciana Labate, E Boniello, Onofrio Resta, Giovanna Elisiana Carpagnano, Vitaliano Nicola Quaranta, Paola Pierucci, Enrico Buonamico |
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Rok vydání: | 2020 |
Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Single Center Respiratory Intermediate Care Unit law.invention 03 medical and health sciences 0302 clinical medicine law Risk Factors Intensive care medicine Humans COVID-19 ICU Transfer Risk Factors 030212 general & internal medicine Respiratory system Pandemics Retrospective Studies COVID-19 Management Italy business.industry SARS-CoV-2 Mortality rate COVID-19 medicine.disease Intensive care unit Pneumonia Intensive Care Units 030228 respiratory system Emergency medicine Original Article Observational study business Respiratory Insufficiency Intermediate care |
Zdroj: | Respiratory Investigation |
ISSN: | 2212-5353 |
Popis: | Background Patients hospitalized for COVID-19-related pneumonia often need several degrees of ventilatory support, which are performed between Respiratory Intermediate Care Units (RICUs) and Intensive Care Units (ICUs), and which depend on the severity of acute respiratory distress syndrome. There is no firm consensus on transfer predictors from the RICU to the ICU. Methods In this retrospective observational single center study, we evaluated 96 COVID-19 patients referred to the RICU for acute respiratory failure (ARF) according to their transferal to the ICU or their stay at the RICU. We compared demographic data, baseline laboratory profile, and final clinical outcomes to identify early risk factors for transfer. Results The best predictors for transfer to the ICU were elevated C-reactive protein and lymphopenia. The mortality rate was lower in the RICU than in the ICU, where transferred patients who died were mostly younger men and with less comorbidities than those in the RICU. Conclusions Few inflammatory markers can predict the need for transfer from the RICU to the ICU. Due to the ongoing COVID-19 pandemic, we urge better clinical stratification by early and meaningful profiles in patients admitted to the RICU who are at risk of transferal to the ICU. |
Databáze: | OpenAIRE |
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