Laparoscopic Gastric Bypass with Silicone Band in a Pig Model: Prevention of Anastomotic Dilatation – Feasibility Study
| Autor: | Gian Mattia Del Genio, Federico Cuenca Abente, Michel Gagner, Diego Bertani, Kazuki Ueda, Ahmad Assalia, David Nocca, Thomas Rogula |
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| Přispěvatelé: | Nocca, D, Gagner, M, Abente, Fc, DEL GENIO, Gianmattia, Ueda, K, Assalia, A, Rogula, T, Bertani, D. |
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Swine Endocrinology Diabetes and Metabolism Gastric Bypass Silicones Laparoscopic gastric bypass Anastomosis Sensitivity and Specificity Random Allocation chemistry.chemical_compound Port (medical) Silicone Risk Factors Weight loss medicine Animals Gastric Balloon Nutrition and Dietetics Equipment Safety business.industry Mortality rate Anastomosis Roux-en-Y Equipment Design Obesity Morbid Surgery Survival Rate Disease Models Animal Catheter chemistry Anesthesia Feasibility Studies Female Laparoscopy medicine.symptom Pouch business Dilatation Pathologic |
| Zdroj: | Obesity Surgery. 15:523-527 |
| ISSN: | 1708-0428 0960-8923 |
| DOI: | 10.1381/0960892053723303 |
| Popis: | Background: Morbid obesity has become a major global health problem. Surgery remains the only effective treatment for patients with severe obesity, because diet reduction methods and pharmacologic agents have not resulted in long-term weight reduction. Gastric bypass (GBP) can provide adequate weight loss, but after some years, dilatation of the gastric pouch and outlet may lead to weight regain by allowing the patient to increase food intake. Methods: 2 groups of 6 pigs underwent laparoscopic GBP. In the first group, a non-adjustable silicone band (Proring®-band, IOC, Innovative Obesity Care, Saint Etienne, France) was positioned 1 cm proximal to the gastrojejunal anastomosis. In the second group, the device used to stabilize the gastric pouch was an adjustable silicone band (Mid-band®, Medical Innovation Developpement, Villeurbanne, France). Weight loss, complications and histological reaction were evaluated after 3 months. Results: Mortality rate was 25% (cardiac arrythmia in 2 pigs). Conversion rate was 25%. The positioning of the band was more difficult with the Mid-band® because of its larger size and the presence of the catheter. The average weight change in the Proring® group was 15.8 kg (3.5–25.1 kg), and in the Mid-band® group was 12.0 kg (6.2–15.1 kg). Morbidity consisted of one intragastric migration of the Proring® band into the gastrojejunal anastomosis, and one infection of the port in the Mid-band® group treated by removal of the port and antibiotics. Conclusion: Use of silicone devices may be safe and effective in the prevention of pouch or outlet dilatation after GBP. |
| Databáze: | OpenAIRE |
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