Kinetics of protein modification reactions. Plot of fractional enzyme activity versus extent of protein modification in cases where all modifiable groups are essential for enzyme activity

Autor:	E T Rakitzis
Rok vydání:	1984
Předmět:	chemistry.chemical_classification Binding Sites biology Stereochemistry Kinetics Proteins Active site Single group Cell Biology Biochemistry Enzyme assay Enzymes Enzyme chemistry Enzyme system Posttranslational modification biology.protein Binding site Molecular Biology Research Article
Zdroj:	Biochemical Journal. 223:259-262
ISSN:	1470-8728 0264-6021
DOI:	10.1042/bj2230259
Popis:	The plot of fractional enzyme activity versus extent of protein modification, for cases where all enzyme modifiable groups of a certain kind are essential for activity, is found to be nearly independent of the number, per enzyme active site, of modifiable groups involved. Such plots usually, by a fallacious extension of the initial portion of the plot on the extent-of-modification axis, are interpreted to mean the modification of one single group per enzyme active site (or per enzyme molecule). The possible relevance of these findings to cases in the literature is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac8dfb19c2ad8541abff2e492c1a485 https://doi.org/10.1042/bj2230259 Zobrazit plný text záznamu