Adverse changes in left ventricular structure begin at normotensive systolic blood pressures: a high resolution MRI study
Autor: | Stuart A. Cook, Declan P. O'Regan, Antonio de Marvao, Daniel Rueckert, Wenzhe Shi, Timothy J W Dawes, Giuliana Durighel |
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Rok vydání: | 2015 |
Předmět: |
Medicine(all)
medicine.medical_specialty Left ventricular structure Radiological and Ultrasound Technology business.industry Cardiomyopathy medicine.disease Essential hypertension 030218 nuclear medicine & medical imaging 3. Good health Muscle hypertrophy 03 medical and health sciences 0302 clinical medicine Blood pressure Afterload Internal medicine medicine Cardiology Radiology Nuclear Medicine and imaging Risk factor Moderated Poster Presentation Cardiology and Cardiovascular Medicine business Angiology |
Zdroj: | Journal of Cardiovascular Magnetic Resonance |
ISSN: | 1532-429X |
Popis: | Background The prevalence of hypertension has doubled over the previous decade and represents a significant public health problem worldwide. Excess cardiovascular risk due to increased blood pressure shows no evidence of a threshold to at least 115/75 mmHg. Left ventricular (LV) hypertrophy has a strong association with essential hypertension and is an independent risk factor for mortality. However, there is little data on whether systolic blood pressure (SBP) influences LV morphology and function in a healthy population. Furthermore it is not clear if any phenotypical changes are part of an adaptive response to increasing afterload or the beginning of a maladaptive process that ultimately leads to cardiomyopathy. |
Databáze: | OpenAIRE |
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