Lymphoma presenting as a parotid tumour: a population-based study of diagnosis, treatment and outcome on behalf of the Scotland and Newcastle Lymphoma Group
| Autor: | C.W. Tiplady, S.J. Proctor, P. Arullendran, J. M. White, P.R.A. Taylor |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Lymphoma Population Disease Diagnosis Differential International Prognostic Index Lymphopenia hemic and lymphatic diseases Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Registries Stage (cooking) education Aged Neoplasm Staging Aged 80 and over education.field_of_study business.industry Lymphoma Non-Hodgkin Parotidectomy Middle Aged Prognosis medicine.disease Hodgkin Disease Survival Analysis Parotid Neoplasms Parotid gland Surgery Population based study medicine.anatomical_structure Scotland Oncology Female business |
| Zdroj: | Clinical Oncology. 16:414-419 |
| ISSN: | 0936-6555 |
| DOI: | 10.1016/j.clon.2004.03.010 |
| Popis: | Aims Lymphoma presenting as a parotid tumour is rare. Previous published studies have been small and have not characterised fully the nature of lymphoma presenting this way. We studied the clinical features, diagnosis, prognosis and treatment in a patient group identified from the Scotland and Newcastle Lymphoma Registry, which is a prospectively collected population-based register of consecutive cases of lymphoma since 1979. Materials and methods The study includes all patients with a biopsy-proven lymphoma in the parotid gland as the first presentation of their disease. Results Of 136 cases identified, 128 had non-Hodgkin's lymphoma (representing 1.5% of the 8499 non-Hodgkin's lymphomas in the registry) and eight had Hodgkin's disease (0.3% of the 2716 cases registered). Female to male ratio was 1.3 : 1, and median age was 69 years (range 19–94 years). Fifty-six per cent of patients had stage I, 16% had stage II, 11% had stage III and 17% had stage IV disease. Diagnostic method was recorded in 81 cases; 47 of these were by parotidectomy. Overall median survival was 90 months, with a 5-year survival of 54%, but there was substantial variation according to age, grade, stage and International Prognostic Index (IPI). Diagnosis was often made by unnecessary major facial surgery, which could be avoided in many cases. Conclusion Treatment should be directed by standard practice for lymphoma according to stage and histological classification. |
| Databáze: | OpenAIRE |
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