| Popis: |
Days for RT112 xenografts to treble in volume and body weights and treatment of Ku80KD xenografts. A) Days for xenografts to treble in volume (PAN+IR vs IR, p=0.06). Skin overlying the xenograft developed ulceration in two mice treated with IR alone and four mice in the PAN+IR group, beyond the time to treble tumour volume; B) Body weight in mice carrying RT112 xenografts, vehicle (n=5), PAN (n=7), PAN+IR (n=6) or IR alone (n=6); C) Mouse body weights in mice carrying 30% KuKD xenografts for vehicle (n=4), PAN (n=6), PAN+IR (n=6) or IR alone (n=6); D) Ku80 knock-down cells express approximately 70% protein; E) Treatment of Ku80KD xenograft mice. |
