Head-to-Head Comparison of EQ-5D-3L and EQ-5D-5L Health Values
| Autor: | Anna Selivanova, Paul F M Krabbe, Erik Buskens |
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| Přispěvatelé: | Methods in Medicines evaluation & Outcomes research (M2O), Value, Affordability and Sustainability (VALUE) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Head to head Health Status Population EUROQOL EQ-5D PREFERENCES Logistic regression 5-LEVEL VERSION DISCRETE-CHOICE EXPERIMENT 03 medical and health sciences Young Adult 0302 clinical medicine EQ-5D Reference Values QUALITY-OF-LIFE Surveys and Questionnaires Statistics medicine Humans 030212 general & internal medicine Original Research Article education Mathematics Aged Netherlands Pharmacology Discrete choice education.field_of_study Models Statistical DUTCH TARIFF 030503 health policy & services Health Policy Public health Public Health Environmental and Occupational Health Middle Aged Health states STANDARD EQ-5D VALUE SETS STATES Pairwise comparison Female 0305 other medical science PATIENT GROUPS |
| Zdroj: | Pharmacoeconomics Pharmacoeconomics, 36(6), 715-725. ADIS INT LTD |
| ISSN: | 1179-2027 1170-7690 |
| Popis: | Background The EQ-5D is a widely used preference-based instrument to measure health-related quality of life. Some methodological drawbacks of its three-level version (EQ-5D-3L) prompted development of a new format (EQ-5D-5L). There is no clear evidence that the new format outperforms the standard version. Objective The objective of this study was to make a head-to-head comparison of the EQ-5D-3L and EQ-5D-5L in a discrete choice model setting giving special attention to the consistency and logical ordering of coefficients for the attribute levels and to the differences in health-state values. Methods Using efficient designs, 240 pairs of EQ-5D-3L health states and 240 pairs of EQ-5D-5L health states were generated in a pairwise choice format. The study included 3698 Dutch general population respondents, analyzed their responses using a conditional logit model, and compared the values elicited by EQ-5D-3L and EQ-5D-5L for different health states. Results No inconsistencies or illogical ordering of level coefficients were observed in either version. The proportion of severe health states with low values was higher in the EQ-5D-5L than in the EQ-5D-3L, and the proportion of mild/moderate states was lower in the EQ-5D-5L than in the EQ-5D-3L. Moreover, differences were observed in the relative weights of the attributes. Conclusion Overall distribution of health-state values derived from a large representative sample using the same measurement framework for both versions showed differences between the EQ-5D-3L and EQ-5D-5L. However, even small differences in the phrasing (language) of the descriptive system or in the valuation protocol can produce differences in values between these two versions. |
| Databáze: | OpenAIRE |
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