Self-sampling is appropriate for detection of Staphylococcus aureus: a validation study
| Autor: | Jan Kluytmans, Brigitte A. G. L. van Cleef, Marianne Ferket, Miranda van Rijen |
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| Přispěvatelé: | Medical Microbiology and Infection Prevention, CCA - Immuno-pathogenesis |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Validation study Veterinary medicine Staphylcococcus aureus MRSA medicine.disease_cause lcsh:Infectious and parasitic diseases Random order Cohen's kappa Internal medicine Validation medicine Pharmacology (medical) lcsh:RC109-216 business.industry Healthy population Research Public Health Environmental and Occupational Health Self-sampling Infectious Diseases Carriage Nasal Swab Staphylococcus aureus business Self sampling |
| Zdroj: | Antimicrobial Resistance and Infection Control, Vol 1, Iss 1, p 34 (2012) Antimicrobial Resistance and Infection Control, 1:34. BioMed Central van Cleef, B A, van Rijen, M M L, Ferket, M & Kluijtmans, J A J W 2012, ' Self-sampling is appropriate for detection of Staphylococcus aureus: a validation study ', Antimicrobial Resistance and Infection Control, vol. 1, 34 . https://doi.org/10.1186/2047-2994-1-34 Antimicrobial Resistance and Infection Control |
| ISSN: | 2047-2994 |
| Popis: | Background Studies frequently use nasal swabs to determine Staphylococcus aureus carriage. Self-sampling would be extremely useful in an outhospital research situation, but has not been studied in a healthy population. We studied the similarity of self-samples and investigator-samples in nares and pharynxes of healthy study subjects (hospital staff) in the Netherlands. Methods One hundred and five nursing personnel members were sampled 4 times in random order after viewing an instruction paper: 1) nasal self-sample, 2) pharyngeal self-sample, 3) nasal investigator-sample, and 4) pharyngeal investigator-sample. Results For nasal samples, agreement is 93% with a kappa coefficient of 0.85 (95% CI 0.74-0.96), indicating excellent agreement, for pharyngeal samples agreement is 83% and the kappa coefficient is 0.60 (95% CI 0.43-0.76), indicating good agreement. In both sampling sites self-samples even detected more S. aureus than investigator-samples. Conclusions This means that self-samples are appropriate for detection of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. |
| Databáze: | OpenAIRE |
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