Complications of Radiofrequency Ablation for Hepatic Hemangioma: A Multicenter Retrospective Analysis on 291 Cases
| Autor: | Ruize Gao, Shilun Wu, Ruhang Zhu, Shi-Gang Guo, Wenbing Sun, Tao Yin, Jun Gao, Xinliang Kong, Aolei Li, Zong-Hai Xin |
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| Rok vydání: | 2021 |
| Předmět: |
Hepatic Hemangioma
safety Cancer Research medicine.medical_specialty Radiofrequency ablation medicine.medical_treatment Technical success complication multicenter Group B law.invention hepatic hemangioma 03 medical and health sciences 0302 clinical medicine law Retrospective analysis Medicine Adverse effect RC254-282 Original Research business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens Ablation Surgery Oncology 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology radiofrequency ablation (RFA) business Complication |
| Zdroj: | Frontiers in Oncology Frontiers in Oncology, Vol 11 (2021) |
| ISSN: | 2234-943X |
| Popis: | PurposeTo report the complications of radiofrequency ablation (RFA) for hepatic hemangioma.Patients and MethodsInvestigators from six centers performed RFA for hepatic hemangioma and used a standardized follow-up protocol. Data were collected from 291 patients, including 253 patients with hepatic hemangioma 5 to 9.9 cm in diameter (group A) and 38 with hepatic hemangioma ≥ 10 cm (group B). Technical success, complete ablation, and complications attributed to the RFA procedure were reported. Analysis of variance was used to determine whether the major complication rate was related to tumor size or clinical experience.ResultsA total of 304 lesions were treated in 291 patients. Technical success was achieved without adverse events in all cases. A total of 301 lesions were completely ablated, including 265 of 265 (100%) lesions in group A, and 36 of 39 (92.31%) in group B. The rate of technology-related complications was similar in groups A and B (5.14% (13/253) and 13.16% (5/38), respectively; P = 0.121). Moreover, all technology-related complications occurred during the early learning curve period. The rate of hemolysis-related complications in two groups were 83.40% (211/253) and 100% (38/38) (P =0.007) and the systemic inflammatory response syndrome-related complications in two groups were 33.99% (86/253) and 86.84% (33/38) (PConclusionRFA is minimally invasive, safe, and effective for hepatic hemangiomas 5 to 9.9 cm in diameter. More clinical data are needed to confirm the safety of RFA for hepatic hemangiomas ≥ 10 cm. |
| Databáze: | OpenAIRE |
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