Safety and efficiency of flow diverters for treating small intracranial aneurysms: A systematic review and meta-analysis
| Autor: | Haitao Shen, Xiaojun Lu, Gang Chen, Junwei Ma, Xiyang Yao, Haiying Li |
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| Rok vydání: | 2017 |
| Předmět: |
Male
flow diverters medicine.medical_specialty small intracranial aneurysms Pipeline (computing) Biochemistry 030218 nuclear medicine & medical imaging Brain Ischemia 03 medical and health sciences 0302 clinical medicine systematic review medicine Humans Prospective Studies Flow diverter Aged Cerebral Hemorrhage Retrospective Studies business.industry Biochemistry (medical) Endovascular Procedures SILK pipeline Intracranial Aneurysm Cell Biology General Medicine Middle Aged Subarachnoid Hemorrhage Survival Analysis Treatment Outcome Intracranial Embolism Meta-analysis Female Radiology Patient Safety business 030217 neurology & neurosurgery Meta-Analysis |
| Zdroj: | The Journal of International Medical Research |
| ISSN: | 1473-2300 |
| Popis: | Background We evaluated the safety and efficiency of flow diverters (FDs) in treating small intracranial aneurysms (IAs). Materials and Methods We reviewed the literature published in PubMed and EMBASE. R for Project software was used to calculate the complete aneurysm occlusion rates, procedure-related neurologic mortality, procedure-related neurologic morbidity and procedure-related permanent morbidity. Results Ten observational studies were included in this analysis. The complete aneurysm occlusion rate was 84.23% (80.34%–87.76%), the procedure-related neurologic mortality was 0.87% (0.29%–1.74%), the procedure-related neurologic morbidity rate was 5.22% (3.62%–7.1%), the intracerebral haemorrhage rate was 1.42% (0.64%–2.49%), the ischemic rate was 2.35% (1.31%–3.68%), the subarachnoid haemorrhage rate was 0.03% (0%–0.32%) and the procedure-related permanent morbidity was 2.41% (0.81%–4.83%). Conclusions Treatment of small IAs with FDs may be correlated with high complete occlusion rates and low complication rates. Future long-term follow-up randomized trials will determine the optimal treatment for small IAs. |
| Databáze: | OpenAIRE |
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