Peripartum metabolic control in gestational diabetes
| Autor: | Juan F. Cano, Alberto Goday, A. Paya, María Ángeles López-Vílchez, Juan J. Chillarón, Juana A. Flores-Le Roux, Jaume Puig de Dou |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty endocrine system diseases medicine.medical_treatment Hypoglycemia chemistry.chemical_compound Pregnancy Diabetes mellitus medicine Humans Hypoglycemic Agents Insulin Prospective Studies Maternal-Fetal Exchange Glycemic Obstetrics business.industry Neonatal hypoglycemia Infant Newborn nutritional and metabolic diseases Obstetrics and Gynecology Delivery Obstetric medicine.disease female genital diseases and pregnancy complications Gestational diabetes Diabetes Gestational chemistry Female Glycated hemoglobin business |
| Zdroj: | American Journal of Obstetrics and Gynecology. 202:568.e1-568.e6 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/j.ajog.2010.01.064 |
| Popis: | Objective We sought to evaluate intrapartum metabolic control in gestational diabetes mellitus (GDM) patients and maternal factors influencing intrapartum glycemic control and neonatal hypoglycemia risk. Study Design A prospective observational study included 129 women with GDM admitted for delivery. Data collected included maternal intrapartum capillary blood glucose (CBG) and ketonemia, use of insulin, and neonatal hypoglycemia. Results In all, 86% of maternal intrapartum CBG values fell within target range (3.3–7.2 mmol/L) without need for insulin use. There were no cases of maternal hypoglycemia or severe ketosis. Intrapartum CBG >7.2 mmol/L was associated with third-trimester glycated hemoglobin ( P = .02) and lack of endocrinologic follow-up ( P = .04). Risk of neonatal hypoglycemia was related with pregnancy insulin use compared with dietary control (60.5% vs 29.5%; P = .02). Conclusion Peripartum metabolic control in GDM patients was achieved without insulin in most cases. Intrapartum glycemic control was related with third-trimester glycated hemoglobin and with no endocrinologic follow-up. Neonatal hypoglycemia was associated with insulin use during pregnancy. |
| Databáze: | OpenAIRE |
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