| Popis: |
Additional file 1: Table S1. CVD classification code system used in this study. ICD-10 codes (given in brackets) have been adapted to form the categories used in this study. We divided the CVDs into 3 broad categories, namely ischemic heart diseases, cerebrovascular accidents, and other heart diseases, which included 7 sub-categories, Table S2. Distribution of climate variables based on population characteristics, Figure S1. Comparison of the Tapp-mortality association in models with varying knot placements. Model 1 has 2 equally placed knots, model2 has 3 knots at the 5th, 50th and 95th percentile of the Tapp model3 has 3 knots at the 25th, 50th and 75th percentile and model 4 has 2 knots on the 5th and 95th percentile of the Tapp, Figure S2. Individual exposure-response associations for the 4 models depicted in figure S1, Figure S3. Comparison of the exposure-response association assuming either a Quasi-poisson or conditional logistic regression with binomial likelihood, such as the one we used, Figure S4. Comparison of the exposure-response association using the complete 10 year data set with cases only from the cardiology department for 2011-2015 and from both the cardiology department and all other departments for 2016-2020 vs using only 5 year data with cases from all the departments from 2016-2020, Figure S5. Annual trends in CVD admissions and mortality, Figure S6. 3D- model depicting the RR for the lagged exposure-response association, Figure S7. Comparison of the exposure-response association using the complete 10 year data set vs restricting it to patients who spent less than 10 days in hospital. The black line depicts the overall association while the grey line depicts the patients who spent less than 10 days admitted to hospital before dying, Figure S8. Exposure-response association at different lag days. a.) 1 day, b.) 5 days, c.) 10 days and d.) 20 days, Figure S9. The role of co-morbidities in the exposure-response association. a.) population with co-morbidities and b.) Population without co-morbidities, Figure S11. Comparison of daily Tapp values from the two weather stations we used in our analysis, namely Cuddalore and Puducherry, Figure S12. Comparison of daily Tapp values from the two weather stations we used in our analysis, namely Cuddalore and Puducherry, along with the average of both which we used in our model (depicted in black). |
