Effect of weight loss on renal function in overweight and obese patients with heart failure
| Autor: | Tamara B. Horwich, Marjan Motie, Lorraine S. Evangelista, Josiah Hoi, Dawn Lombardo, Gregg C. Fonarow, Michele A. Hamilton |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Kidney Disease Endocrinology Diabetes and Metabolism Hyperfiltration 030232 urology & nephrology 030204 cardiovascular system & hematology Overweight Cardiovascular urologic and male genital diseases Kidney chemistry.chemical_compound 0302 clinical medicine Weight loss 80 and over Medicine Aged 80 and over Metabolic Syndrome Diabetes General Medicine Middle Aged Weight Reduction Programs medicine.anatomical_structure Heart Disease Body Composition Female medicine.symptom Waist Circumference Glomerular Filtration Rate Adult medicine.medical_specialty Clinical Sciences Urology Renal and urogenital Renal function and over Article Diabetes Complications 03 medical and health sciences Endocrinology & Metabolism Clinical Research Diabetes mellitus Internal medicine Weight Loss Internal Medicine Humans Obesity Metabolic and endocrine Nutrition Aged Heart Failure Creatinine business.industry Prevention medicine.disease Endocrinology chemistry Heart failure Metabolic syndrome business |
| Zdroj: | Motie, M; Evangelista, LS; Lombardo, D; Hoi, J; Horwich, TB; Hamilton, M; et al.(2017). Effect of weight loss on renal function in overweight and obese patients with heart failure.. Diabetes & metabolic syndrome, 11(2), 95-98. doi: 10.1016/j.dsx.2016.06.026. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7sb3f7mm Diabetes & metabolic syndrome, vol 11, iss 2 |
| Popis: | AimsThe effect of intentional weight loss on glomerular filtration rate (GFR) in overweight and obese patients with heart failure (HF), diabetes mellitus (DM) and/or metabolic syndrome (MS) has not been studied. The purpose of the present study is to assess the short term effects of intentional weight loss on renal function in this population.Materials and methodsFifty nine patients were recruited to participate in a 3-month intensive behavioral weight management intervention and received one of two standard structured energy-restricted meal plans (1200 or 1500kcal/day) based on their computed calorie deficit. Weight and renal function (serum creatinine, BUN and estimated glomerular filtration rate based on two formulas - Modification in Renal Disease Study (MDRD), and modified version of Cockcroft-Gault formula reported by Salazar Corcoran for obese patients (absolute and relative formulas) - were evaluated at baseline and at 3 months.ResultsParticipants had eGFR in the normal range at baseline and lost an average of 7.56±14.9 pounds (p |
| Databáze: | OpenAIRE |
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