4,4′-Methylenedianiline-induced hepatitis in an industrial worker: Case report and review of the literature
| Autor: | Andreas Xanthis, Sofia Karabatsou, Dimitrios Koliouskas, Tsiaousi E, Prodromos Hytiroglou, Olga Giouleme, Marios Katsaros |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty 4 4'-Methylenedianiline Health Toxicology and Mutagenesis Treatment outcome Toxicology Methylprednisolone chemistry.chemical_compound Liver Function Tests medicine Humans Liver damage Intensive care medicine Hepatitis Aniline Compounds business.industry Clinical course Hepatotoxin General Medicine Allergens medicine.disease Chemical used Surgery Occupational Diseases Treatment Outcome Liver chemistry Acute Disease Chemical and Drug Induced Liver Injury business |
| Zdroj: | Human & Experimental Toxicology. 30:762-767 |
| ISSN: | 1477-0903 0960-3271 |
| Popis: | 4,4′-Methylenedianiline (MDA) is a chemical used in manufacturing and insulation processes and is a well-known hepatotoxin. We report the case of a 42-year-old construction-site worker who was accidentally exposed to large amounts of MDA and developed acute liver damage. The clinical course is described, with particular emphasis on the timely identification of the underlying cause and prompt management that led to an uneventful recovery. We review the relevant literature and discuss the safety measures necessary to minimize similar occupational hazards in industrial workers. |
| Databáze: | OpenAIRE |
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