SK channels and the varieties of slow after-hyperpolarizations in neurons

Autor:	Fivos Vogalis, Barrie Lancaster, Johan F. Storm
Rok vydání:	2003
Předmět:	Neurons Membrane potential Potassium Channels Small-Conductance Calcium-Activated Potassium Channels Chemistry General Neuroscience Cell Membrane Action Potentials Apamin Potassium channel SK channel Potassium Channels Calcium-Activated Protein Subunits chemistry.chemical_compound Slow afterhyperpolarization Animals Humans Calcium Calcium Signaling Neuroscience Ion channel
Zdroj:	European Journal of Neuroscience. 18:3155-3166
ISSN:	1460-9568 0953-816X
Popis:	Action potentials and associated Ca2+ influx can be followed by slow after-hyperpolarizations (sAHPs) caused by a voltage-insensitive, Ca2+-dependent K+ current. Slow AHPs are a widespread phenomenon in mammalian (including human) neurons and are present in both peripheral and central nervous systems. Although, the molecular identity of ion channels responsible for common membrane potential mechanisms has been largely determined, the nature of the channels that underlie the sAHPs in neurons, both in the brain and in the periphery, remains unresolved. This short review discusses why there is no clear molecular candidate for sAHPs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a878b495eeb35211ea2ccdecce81705 https://doi.org/10.1111/j.1460-9568.2003.03040.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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