Diffuse normolipemic plane xanthoma in a 9-year-old boy
| Autor: | Kristina Zappel, Maja A. Hofmann, Ulrike Blume-Peytavi, Uwe Trefzer, Helga Albrecht-Nebe, Heike Audring, Wolfram Sterry |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Paraproteinemia Pathology medicine.medical_specialty CD68 business.industry Biopsy Antigens Differentiation Myelomonocytic Dermatology Xanthoma medicine.disease Skin Diseases Lymphoma Leukemia Myeloproliferative Disorders Touton giant cell Antigens CD Pediatrics Perinatology and Child Health medicine Xanthomatosis Humans business Child Plane xanthoma |
| Zdroj: | Pediatric dermatology. 22(2) |
| ISSN: | 0736-8046 |
| Popis: | Normolipemic plane xanthoma normally occurs in adults. We report the atypical instance of a 9-year-old boy who developed disseminated, flat, yellow-brown plaques up to 2 to 3 cm without any complaints. The histology showed the hallmarks of xanthoma, including the presence of CD68+ foam cells and Touton giant cells. No systemic involvement or lipid disorders were evident. It is important to perform regular follow-up of these patients because normolipemic plane xanthoma often precedes myeloproliferative disorders such as leukemia, paraproteinemia, or lymphoma. |
| Databáze: | OpenAIRE |
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