Fatal SARS-CoV-2 infection in a renal transplant recipient
| Autor: | Ahmet Burak Dirim, Ozgur Akin Oto, Günseli Orhun, Ali Riza Ucar, Arif Atahan Çağatay, Nurana Garayeva, Erol Demir, Aydin Turkmen, Alpay Alibeyoğlu, Halil Yazici, Seda Safak |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Nephrology
medicine.medical_specialty Multiple Organ Failure medicine.medical_treatment Pneumonia Viral 030232 urology & nephrology Case Report Azithromycin 030204 cardiovascular system & hematology Favipiravir Antiviral Agents Asymptomatic Betacoronavirus 03 medical and health sciences Fatal Outcome 0302 clinical medicine Diabetes mellitus Internal medicine medicine Humans Pandemics Kidney transplantation Clinical Deterioration SARS-CoV-2 business.industry COVID-19 Cancer Renal transplantation Immunosuppression General Medicine Middle Aged medicine.disease Kidney Transplantation Respiration Artificial Treatment Macrophage activation syndrome Kidney Failure Chronic Female medicine.symptom Coronavirus Infections Tomography X-Ray Computed business Immunosuppressive Agents Hydroxychloroquine |
| Zdroj: | CEN Case Reports |
| ISSN: | 2192-4449 |
| Popis: | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) caused a pandemic that first discovered in Wuhan, China. While 10% of the patients have asymptomatic infection, 15-20% have lung involvement, 5-10% have multiple organ failure, and macrophage activation syndrome. Chronic respiratory diseases, diabetes mellitus, hypertension, and cancer are risk factors for mortality. Prognosis or optimal treatment strategy for renal transplant recipients in SARS-CoV-2 infection is still unknown. Besides fatal cases, there were also milder case reports. In addition, COVID-19 treatment and the maintenance immunosuppression strategy is still under debate. Antiviral therapies and drug interactions are special topics for these patients. To the best of our knowledge, favipiravir and anti-cytokine treatments have not been previously reported in a kidney transplant recipient with SARS-CoV-2 infection before. We report a case of SARS-CoV-2 infection in a kidney transplant recipient with fatal outcomes. |
| Databáze: | OpenAIRE |
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