Expression of proopiomelanocortin (POMC) in the cerebral ganglion and ovary of a protochordate
| Autor: | Maddalena Sturla, Simona Candiani, Andrea Gallinelli, Ma Masini, Mario Pestarino, Fabio Facchinetti |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
Cytoplasm
endocrine system medicine.medical_specialty Pro-Opiomelanocortin Physiology Ovary In situ hybridization Biology Biochemistry Oogenesis Cellular and Molecular Neuroscience Nerve Fibers Endocrinology Ovarian Follicle cortincerebral ganglio Internal medicine medicine Animals pro-opiomelano Urochordata In Situ Hybridization Neurons Regulation of gene expression Messenger RNA digestive oral and skin physiology Epithelial Cells Ribonuclease Pancreatic biology.organism_classification Ganglia Invertebrate Ganglion Cell biology Styela plicata medicine.anatomical_structure Gene Expression Regulation nervous system Oocytes Female hormones hormone substitutes and hormone antagonists |
| Zdroj: | ResearcherID |
| Popis: | The distribution of neurones expressing POMC mRNA in the cerebral ganglion of the protochordate ascidian, Styela plicata, was investigated using a non-radioactive in situ hybridization technique. Nerve cell bodies of mono and bipolar types expressing POMC mRNA, were observed mainly in the outer layer of the ganglion. Discrete groups of neurones containing POMC mRNA were also localized in the inner portion of the ganglion, and few small monopolar perykaria expressing POMC mRNA were visible at the emergence of the main nerve trunks. POMC mRNA labeling was also found at level of the cytoplasm of previtellogenic and vitellogenic oocytes, and of follicular cells. Our results demonstrate the expression of one or more genes in the cerebral ganglion and ovary, that may be similar to one or more regions of the mammalian POMC gene. Therefore POMC-related molecules seem to be involved in neuromodulatory pathways and regulatory mechanisms of the oogenesis of ascidians. |
| Databáze: | OpenAIRE |
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