A higher preconceptional paternal body mass index influences fertilization rate and preimplantation embryo development
| Autor: | Jeffrey Hoek, Sam Schoenmakers, Régine P.M. Steegers-Theunissen, Linette van Duijn, Sten P. Willemsen, Eva S van Marion, Esther B Baart, Joop S.E. Laven |
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| Přispěvatelé: | Obstetrics & Gynecology, Epidemiology, Developmental Biology |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Urology Endocrinology Diabetes and Metabolism medicine.medical_treatment Embryonic Development Fertilization in Vitro Overweight Intracytoplasmic sperm injection Body Mass Index Cohort Studies Endocrinology SDG 3 - Good Health and Well-being Pregnancy medicine Humans Prospective Studies Retrospective Studies In vitro fertilisation Obstetrics business.industry Embryo Sperm Reproductive Medicine Fertilization Female medicine.symptom Live birth business Body mass index Embryo quality |
| Zdroj: | Andrology, 10(3), 486-494. John Wiley & Sons Inc. |
| ISSN: | 2047-2927 2047-2919 |
| Popis: | Background: Obesity is a worldwide problem affecting the health of millions of people throughout the life course. Studies reveal that obesity impairs sperm parameters and epigenetics, potentially influencing embryonic development. Objective: To investigate the association between preconceptional paternal body mass index (BMI) and embryo morphokinetics using a time-lapse incubator and in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) outcomes. Materials and methods: Participants were recruited from a tertiary hospital in this prospective periconceptional cohort study. A total of 211 men were included: 86 with normal weight (BMI |
| Databáze: | OpenAIRE |
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