Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
| Autor: | Helia Bello-Toledo, Daniela Fuentes-Rodríguez, Gabriela Sánchez-Sanhueza |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Chemistry
business.industry copper nanoparticles Nanoparticle chemistry.chemical_element Dentistry 02 engineering and technology 010501 environmental sciences 021001 nanoscience & nanotechnology Antimicrobial 01 natural sciences Copper antibacterial endodontics 0210 nano-technology business 0105 earth and related environmental sciences |
| Zdroj: | International journal of odontostomatology v.10 n.3 2016 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Copper was registered as the first solid antimicrobial material. Its availability makes it an important option as an antibacterial agent. At nanoparticle size it does not exceed 100 nm, allowing close interaction with microbial membranes, enhancing its effect even more. Copper generates toxic hydroxyl radicals that damage cell membranes of Gram-negative and Gram-positive bacteria, among the latter, Enterococcus faecalis, which are present in infected radicular canals. Synthesis of metal nanoparticles with antimicrobial properties has become a viable alternative and has promising applications in the fight against pathogenic microorganisms. Furthermore, the use of some polymers to stabilize nanoparticles increases their release time and may as well decrease the risk of bacterial recolonization and biofilm formation within the ducts, enhancing the antimicrobial properties of these compounds.The aim of this article is to conduct a systematic review of the literature on antimicrobial copper nanoparticles, their current applications and their potential use in the area of oral health, specifically in the field of endodontics. |
| Databáze: | OpenAIRE |
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