The epidemiology of residual Plasmodium falciparum malaria transmission and infection burden in an African city with high coverage of multiple vector control measures

Autor: Daniel Msellemu, Neil F. Lobo, Zacharia Mtema, Chris Drakeley, Yeromin P. Mlacha, Gerry F. Killeen, Hagai I. Namango, Nicodem J. Govella, Silas Majambere, Stefan Dongus, Prosper P Chaki, Samson S. Kiware, Alex J. Ntamatungiro, Victoria M. Mwakalinga
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
Plasmodium
Mosquito Control
Long-lasting insecticidal net
Tanzania
0302 clinical medicine
Mosquito
Epidemiology
Prevalence
030212 general & internal medicine
Longitudinal Studies
Artemisinin
Malaria
Falciparum

Child
2. Zero hunger
Aged
80 and over

Middle Aged
3. Good health
Chronic infection
Infectious Diseases
Child
Preschool

Female
Larval source management
medicine.drug
Adult
medicine.medical_specialty
Adolescent
030231 tropical medicine
wc_765
Biology
wa_110
03 medical and health sciences
Young Adult
Internal medicine
qx_600
Anopheles
parasitic diseases
medicine
Disease Transmission
Infectious

Animals
Humans
Aged
Research
Infant
Newborn

wa_240
Infant
Plasmodium falciparum
Odds ratio
biology.organism_classification
medicine.disease
Confidence interval
Vector control
Malaria
Cross-Sectional Studies
Window screening
qx_135
Immunology
Tropical medicine
Africa
Housing
Parasitology
Zdroj: Malaria Journal
ISSN: 1475-2875
Popis: Background In the Tanzanian city of Dar es Salaam, high coverage of long-lasting insecticidal nets (LLINs), larvicide application (LA) and mosquito-proofed housing, was complemented with improved access to artemisinin-based combination therapy and rapid diagnostic tests by the end of 2012. Methods Three rounds of city-wide, cluster-sampled cross-sectional surveys of malaria parasite infection status, spanning 2010 to 2012, were complemented by two series of high-resolution, longitudinal surveys of vector density. Results Larvicide application using a granule formulation of Bacillus thuringiensis var. israelensis (Bti) had no effect upon either vector density (P = 0.820) or infection prevalence (P = 0.325) when managed by a private-sector contractor. Infection prevalence rebounded back to 13.8 % in 2010, compared with
Databáze: OpenAIRE