Additional file 1 of CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110

Autor: Domínguez, Juan Manuel, Pérez-Chacón, Gema, Guillén, María José, Muñoz-Alonso, María José, Somovilla-Crespo, Beatriz, Danay Cibrián, Acosta-Iborra, Bárbara, Adrados, Magdalena, Muñoz-Calleja, Cecilia, Cuevas, Carmen, Sánchez-Madrid, Francisco, Avilés, Pablo, Zapata, Juan M.
Rok vydání: 2020
DOI: 10.6084/m9.figshare.12097239.v1
Popis: Additional file 1: Supplementary Materials and Methods, Table S1. Anti-proliferative activity of PM050489 in CD13 positive and negative cell lines. Figure S1. Immunohistochemistry analysis of CD13 expression in tumor samples. Figure S2. Chromatography analysis of TEA1/8 mAb and MI130110. Figure S3. Immunofluorescence analysis of the nuclear membrane and chromosome condensation. Figure S4. Flow cytometry analysis of cells used in xenograft models. Figure S4. Evolution of HT1080 tumor volumes at 4 given days. Figure S4. Evolution of HT1080 tumor volumes at 4 given days in MI130110-treated xenografted mice.
Databáze: OpenAIRE