SF3B4 Depletion Retards the Growth of A549 Non-Small Cell Lung Cancer Cells via UBE4B-Mediated Regulation of p53/p21 and p27 Expression

Autor:	Hyungmin Kim, Jeehan Lee, Soon-Young Jung, Hye Hyeon Yun, Jeong-Heon Ko, Jeong-Hwa Lee
Rok vydání:	2022
Předmět:	Cyclin-Dependent Kinase Inhibitor p21 Lung Neoplasms Ubiquitin-Protein Ligases Cell Biology General Medicine Carcinoma Non-Small-Cell Lung Cell Line Tumor RNA Precursors Humans RNA Splicing Factors RNA Small Interfering Tumor Suppressor Protein p53 Molecular Biology Cell Proliferation
Zdroj:	Molecules and cells. 45(10)
ISSN:	0219-1032
Popis:	Splicing factor B subunit 4 (SF3B4), a component of the U2-pre-mRNA spliceosomal complex, contributes to tumorigenesis in several types of tumors. However, the oncogenic potential of SF3B4 in lung cancer has not yet been determined. The
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a72bdcc174316e02476d0be8ae18ed0 https://pubmed.ncbi.nlm.nih.gov/35996826 Zobrazit plný text záznamu