Abnormal hemoglobins in the Negroes of Surinam

Autor: Iwan Guichirit, Claire Liachowitz, Harold W. Brown, Janet Elderkin, Helen M. Ranney
Rok vydání: 1958
Předmět:
Zdroj: The American Journal of Medicine. 24:19-24
ISSN: 0002-9343
DOI: 10.1016/0002-9343(58)90358-9
Popis: 1. 1. A study of the incidence of abnormal hemoglobins among the Djuka population of Surinam revealed an incidence of sickle cell hemoglobin of 15 per cent and an incidence of hemoglobin C of 3 per cent. Two cases interpreted as sickle cell-thalassemia disease indicated the probable presence of the gene for thalassemia in the Djukas. The incidence of sickling and the distribution of the ABO and Rho (D) blood groups were comparable to those found in studies of the West African population; the incidence of hemoglobin C was significantly lower among the Djukas than among Gold Coast Africans. 2. 2. An overall malarial infection rate of 20 per cent was found among the Djukas; 88 per cent of the malarial infections were caused by P. falciparum. The incidence of P. falciparum parasitemia was the same in sicklers as in nonsicklers. The number of children in the study was small [43]; sickling and P. falciparum malaria were found simultaneously in three of these children. 3. 3. A high incidence of hypochromic anemia, presumed to be due to parasites, was encountered.
Databáze: OpenAIRE