Supplementary Figures 1-10 from Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1-Mutated Mouse Mammary Tumors
| Autor: | Sven Rottenberg, Jos Jonkers, Piet Borst, Shridar Ganesan, Mark J. O'Connor, Alan Lau, Niall M.B. Martin, Aaron Cranston, James H. Doroshow, Amal Aly, Jiuping Ji, Ellen Wientjens, Rinske Drost, Serge A. Zander, Liesbeth van Deemter, Wendy Sol, Ute Boon, Ariena Kersbergen, Janneke E. Jaspers |
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| Rok vydání: | 2023 |
| Popis: | PDF file - 1.2MB, This file contains additional data on tumor responses to olaparib treatment (Fig. S1 and S2), pH2AX stainings on treated and untreated tumors (Fig. S3), analysis of mutations in 53BP1 (Fig. S4 and S7B), characterization of cell lines (Fig. S5), RAD51 and 53BP1 IRIFs in tumors and cell lines (Fig. S6 and S7), 53BP1 in topotecan-resistant tumors (Fig. S8) and tumor responses to AZD2461 treatment (Fig. S9 and S10). |
| Databáze: | OpenAIRE |
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