Dynamic contrast enhanced ultrasound for therapy monitoring

Autor: Ross Williams, Paul S. Sheeran, Peter N. Burns, Georg A. Bjarnason, John M. Hudson, Laurent Milot, Charles Tremblay-Darveau
Rok vydání: 2015
Předmět:
Zdroj: European Journal of Radiology. 84:1650-1657
ISSN: 0720-048X
DOI: 10.1016/j.ejrad.2015.05.013
Popis: Quantitative imaging is a crucial component of the assessment of therapies that target the vasculature of angiogenic or inflamed tissue. Dynamic contrast-enhanced ultrasound (DCE-US) using microbubble contrast offers the advantages of being sensitive to perfusion, non-invasive, cost effective and well suited to repeated use at the bedside. Uniquely, it employs an agent that is truly intravascular. This papers reviews the principles and methodology of DCE-US, especially as applied to anti-angiogenic cancer therapies. Reproducibility is an important attribute of such a monitoring method: results are discussed. More recent technical advances in parametric and 3D DCE-US imaging are also summarised and illustrated.
Databáze: OpenAIRE