In vitro antiphagocytic effect of Melia azedarach leaf extracts on mouse peritoneal exudate cells
| Autor: | Ernesto J. Massouh, C.E. Coto, Maria C. Courreges, F.C. Coulombié, Fabián Benencia |
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| Rok vydání: | 1994 |
| Předmět: |
Time Factors
Melia azedarach Phagocytosis In Vitro Techniques Microbiology chemistry.chemical_compound Mice Drug Discovery Macrophage Animals Opsonin Respiratory Burst Pharmacology Mice Inbred BALB C Meliaceae biology Traditional medicine Dose-Response Relationship Drug Plant Extracts Zymosan biology.organism_classification In vitro Respiratory burst chemistry Luminescent Measurements Macrophages Peritoneal |
| Zdroj: | Journal of ethnopharmacology. 43(2) |
| ISSN: | 0378-8741 |
| Popis: | The effect of Melia azedarach L. (Meliaceae) leaf extract on the phagocytic capability and respiratory burst of mouse peritoneal exudate cells was studied. The extract inhibited the phagocytosis of opsonized sheep erythrocytes. This inhibition was both dose- and time-dependent and reverted 48 h after removing the extract from the culture medium. Furthermore, chemiluminescence in treated cells was also impaired using either receptor (opsonized zymosan) or post-receptor (PMA) stimuli. |
| Databáze: | OpenAIRE |
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