Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods
| Autor: | Robert B. Baird, John M. Urban, Andrew J. Mongue, Kamil S. Jaron, Christina N. Hodson, Malte Grewoldt, Simon H. Martin, Laura Ross |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Baird, R B, Urban, J M, Mongue, A J, Jaron, K S, Hodson, C N, Grewoldt, M, Martin, S H & Ross, L 2023, ' Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods ', Molecular Biology and Evolution . https://doi.org/10.1093/molbev/msad148 Baird, R B, Urban, J M, Mongue, A J, Jaron, K S, Hodson, C N, Grewoldt, M, Martin, S H & Ross, L 2023, ' Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods ', Molecular Biology and Evolution, vol. 40, no. 7, msad148 . https://doi.org/10.1093/molbev/msad148 |
| DOI: | 10.1093/molbev/msad148 |
| Popis: | Sex determination is a key developmental process, yet it is remarkably variable across the tree of life. The dipteran family Sciaridae exhibits one of the most unusual sex determination systems in which mothers control offspring sex through selective elimination of paternal X chromosomes. Whereas in some members of the family females produce mixed-sex broods, others such as the dark-winged fungus gnatBradysia coprophilaare monogenic, with females producing single-sex broods. Female-producing females were previously found to be heterozygous for a large X-linked paracentric inversion (X’), which is maternally inherited and absent from male-producing females. Here we assembled and characterized the X’ sequence. As close sequence homology between the X and X’ made identification of the inversion challenging, we developed a k-mer-based approach to bin genomic reads before assembly. We confirmed that the inversion spans most of the X’ chromosome (approximately 55Mb) and encodes around 3500 genes. Analysis of the divergence between the inversion and the homologous region of the X revealed that it originated very recently ( |
| Databáze: | OpenAIRE |
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