Selective maternal culturing to identify group B streptococcal infection

Autor: Marykay Pasnick, Philip B. Mead, Alistair G. S. Philip
Rok vydání: 1980
Předmět:
Zdroj: American Journal of Obstetrics and Gynecology. 138:480-484
ISSN: 0002-9378
DOI: 10.1016/0002-9378(80)90273-2
Popis: During a 5-year period vaginal cultures were obtained from all women with an obstetric history of premature onset of labor or premature rupture of membranes. With these indications, 1,213 (12.7%) of all parturient patients were cultured and 10.2% of those cultured were colonized with group B beta-hemolytic streptococci. Maternal colonization did not correlate with ABO blood group, although a significantly higher percentage of Rh negative women were colonized (p0.01). During this 5-year period, 20 infants had documented early-onset infection (sepsis or meningitis) with group B beta-hemolytic streptococci. All 10 infants had a maternal history of premature onset of labor and/or premature rupture of membranes. Mothers of eight infants were cultured and seven of these cultures were positive. Approximately one of every 20 infants designated at high risk actually developed early-onset disease. Selective maternal culturing effectively identifies those infants as risk for early-onset group B streptococcal disease.
Databáze: OpenAIRE