Oestrogen-induced proteins and uterine growth in the androgenized female rat
| Autor: | R. T. Lobl, B. Brumberger, P. Trotta |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Testosterone propionate
medicine.medical_specialty medicine.drug_class Endocrinology Diabetes and Metabolism Uterus Tritium Andrology Anovulation chemistry.chemical_compound Endocrinology Leucine Internal medicine medicine Endocrine system Animals Carbon Radioisotopes Castration Testosterone Estrous cycle Estradiol urogenital system business.industry Organ Size medicine.disease Rats medicine.anatomical_structure chemistry Estrogen Protein Biosynthesis Androgens Female business hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | The Journal of endocrinology. 60(2) |
| ISSN: | 0022-0795 |
| Popis: | Administration of testosterone propionate to neonatal female rats has shown an induced syndrome of sterility characterized by acyolicity and anovulation. This study examines the ability of the uterus of androgenized female rats to respond to estradiol by measuring changes in weight and formation of specific estrogen-induced proteins. Results indicate that uteri from diestrus and androgenized female rats responded to estrogen by the production of estrogen-induced proteins with similar electrophoretic mobility. It is concluded that the uterus from intact androgenized rats is tonically maximally stimulated but after ovariectomy the atrophied uterus is capable of growing in response to estradiol and of producing estrogen-induced proteins with the same electrophoretic mobility as those in normal uteri. |
| Databáze: | OpenAIRE |
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