Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics
| Autor: | Xiaoxian Zhu, Rakesh Pemmada, Himansu Sekhar Nanda, Madhusmita Dash, Vinoy Thomas, Seeram Ramakrishna, Yubin Zhou, Xinsheng Peng, Sanjeev Jain |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 02 engineering and technology Surgical Drape Review coatings Antiviral mechanism medicine.disease_cause lcsh:Technology Virus 03 medical and health sciences Pandemic medicine General Materials Science lcsh:Microscopy nanomaterials 030304 developmental biology Coronavirus lcsh:QC120-168.85 0303 health sciences antiviral products lcsh:QH201-278.5 lcsh:T metal ions and oxides COVID-19 polymeric materials 021001 nanoscience & nanotechnology Virology antiviral lcsh:TA1-2040 lcsh:Descriptive and experimental mechanics Business lcsh:Electrical engineering. Electronics. Nuclear engineering 0210 nano-technology lcsh:Engineering (General). Civil engineering (General) lcsh:TK1-9971 |
| Zdroj: | Materials, Vol 13, Iss 4041, p 4041 (2020) Materials |
| ISSN: | 1996-1944 |
| Popis: | The worldwide, extraordinary outbreak of coronavirus pandemic (i.e., COVID-19) and other emerging viral expansions have drawn particular interest to the design and development of novel antiviral, and viricidal, agents, with a broad-spectrum of antiviral activity. The current indispensable challenge lies in the development of universal virus repudiation systems that are reusable, and capable of inactivating pathogens, thus reducing risk of infection and transmission. In this review, science-based methods, mechanisms, and procedures, which are implemented in obtaining resultant antiviral coated substrates, used in the destruction of the strains of the different viruses, are reviewed. The constituent antiviral members are classified into a few broad groups, such as polymeric materials, metal ions/metal oxides, and functional nanomaterials, based on the type of materials used at the virus contamination sites. The action mode against enveloped viruses was depicted to vindicate the antiviral mechanism. We also disclose hypothesized strategies for development of a universal and reusable virus deactivation system against the emerging COVID-19. In the surge of the current, alarming scenario of SARS-CoV-2 infections, there is a great necessity for developing highly-innovative antiviral agents to work against the viruses. We hypothesize that some of the antiviral coatings discussed here could exert an inhibitive effect on COVID-19, indicated by the results that the coatings succeeded in obtaining against other enveloped viruses. Consequently, the coatings need to be tested and authenticated, to fabricate a wide range of coated antiviral products such as masks, gowns, surgical drapes, textiles, high-touch surfaces, and other personal protective equipment, aimed at extrication from the COVID-19 pandemic. |
| Databáze: | OpenAIRE |
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