Effects of temperature and salinity on bioconcentration and toxicokinetics of permethrin in pyrethroid-resistant Hyalella azteca
| Autor: | Andrew P. Derby, Kara E. Huff Hartz, Neil W. Fuller, Peter F. Landrum, John D. Reeve, Helen C. Poynton, Richard E. Connon, Michael J. Lydy |
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| Rok vydání: | 2021 |
| Předmět: |
Insecticides
Salinity Environmental Engineering Health Toxicology and Mutagenesis Public Health Environmental and Occupational Health Temperature General Medicine General Chemistry Pollution Bioaccumulation Toxicokinetics Pyrethrins Environmental Chemistry Animals Amphipoda Permethrin Water Pollutants Chemical |
| Zdroj: | Chemosphere. 299 |
| ISSN: | 1879-1298 |
| Popis: | Recent studies demonstrated pyrethroid resistance associated with voltage-gated sodium channel mutations in populations of the epibenthic amphipod, Hyalella azteca. Resistant populations were able to tolerate and bioconcentrate pyrethroids at concentrations significantly higher than toxic levels for non-resistant populations. In conjunction with elevated bioconcentration potential, environmental alteration particularly as a result of global climate change is anticipated to significantly alter abiotic parameters including temperature and salinity. These changes are expected to influence uptake and biotransformation of contaminants. Thus, the aims of the current study were a) to examine the bioconcentration potential of permethrin in two pyrethroid-resistant clades of H. azteca and b) assess the influence of temperature and salinity changes on toxicokinetic parameters. Two pyrethroid-resistant clades of H. azteca were exposed to |
| Databáze: | OpenAIRE |
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