Chemical Ligation to Obtain Proteins Comprising Helices with Individual Amino Acid Sequences

Autor:	Tomoko Ishikawa, Mineo Niwa, Shiroh Futaki, Tomoko Asahara, Kouki Kitagawa, Fusayo Kondo, Takeshi Yagami, Yutaka Nakaya, Mika Aoki
Rok vydání:	1999
Předmět:	Models Molecular Circular dichroism Stereochemistry Molecular Sequence Data Clinical Biochemistry Pharmaceutical Science Peptide Biochemistry Protein Structure Secondary Sodium Channels chemistry.chemical_compound Protein structure Drug Discovery Peptide synthesis Animals Amino Acid Sequence Molecular Biology Peptide sequence chemistry.chemical_classification Circular Dichroism Organic Chemistry Peptide sequence tag Proteins Amino acid chemistry Electrophorus Molecular Medicine Chemical ligation Peptides
Zdroj:	Bioorganic & Medicinal Chemistry. 7:187-192
ISSN:	0968-0896
Popis:	Development of the strategies for assembling multiple kinds of peptide segments would give new possibilities for the de novo design of functional proteins. We will introduce our approach for the selective assembly of helical peptide segments on a peptide template to give four-helix-bundle proteins comprising individual helices.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4d0ab279025c5d65fe8ba7189ea7a7 https://doi.org/10.1016/s0968-0896(98)00246-6 Zobrazit plný text záznamu Full Text from ScienceDirect