The hemodynamic effects of intubation during nitroglycerin infusion in severe preeclampsia
| Autor: | Line Leduc, Monica M. Jones, David B. Cotton, J. L. Hawkins, Stephen Longmire, Thomas H. Joyce |
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| Rok vydání: | 1991 |
| Předmět: |
Oncotic pressure
Adult Mean arterial pressure Adolescent medicine.medical_treatment Pregnancy Trimester Third Cardiac index Hemodynamics Obstetric anesthesia Anesthesia General Nitroglycerin Pre-Eclampsia Pregnancy Heart rate medicine Intubation Intratracheal Intubation Anesthesia Obstetrical Humans Pulmonary wedge pressure Infusions Intravenous Blood Volume business.industry Obstetrics and Gynecology General Medicine Blood pressure medicine.anatomical_structure Anesthesia Acute Disease Vascular resistance Drug Evaluation Female business |
| Zdroj: | American journal of obstetrics and gynecology. 164(2) |
| ISSN: | 0002-9378 |
| Popis: | The effectiveness of intravenous nitroglycerin infusion in lowering maternal blood pressure and in blunting the hemodynamic responses to endotracheal intubation was evaluated in six primigravid women with severe preeclampsia. Monitoring consisted of continuous electrocardiogram monitoring, arterial cannulation, and flow-directed pulmonary arterial catheterization in each patient. All patients underwent oxytocin induction of labor and crystalloid and/or colloid expansion to produce a pulmonary capillary wedge pressure of 10 to 15 mm Hg and a colloid osmotic pressure of greater than 17 mm Hg. Intravenous nitroglycerin was administered before induction of general anesthesia. The hemodynamic effects associated with endotracheal intubation revealed a change in the heart rate from 104 +/- 10 to 133 +/- 17 beats/min, an increase in mean arterial pressure from 134 +/- 12 to 164 +/- 32 mm Hg, and an increase in systemic vascular resistance from 1262 +/- 342 to 1351 +/- 259 dynes-sec-cm-5 that was accompanied by a small change in the cardiac index from 4.5 +/- 1.2 to 4.5 +/- 0.9 L.min-1.m-2. |
| Databáze: | OpenAIRE |
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