Predictive Factors for the Need for Additional Humidification During Nasal Continuous Positive Airway Pressure Therapy
| Autor: | Bernard Fleury, Dominique Rakotonanahary, Frédéric Gagnadoux, Nathalie Pelletier-Fleury |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_treatment Positive pressure Critical Care and Intensive Care Medicine Positive-Pressure Respiration Sleep Apnea Syndromes Risk Factors Humans Medicine Prospective Studies Continuous positive airway pressure Prospective cohort study Aged business.industry Uvulopalatopharyngoplasty Humidity Middle Aged medicine.disease Confidence interval Obstructive sleep apnea Apnea–hypopnea index Anesthesia Female Cardiology and Cardiovascular Medicine business Airway |
| Zdroj: | Chest. 119:460-465 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.119.2.460 |
| Popis: | To identify potential risk factors for the need for an additional cold or heated humidifier in nasal continuous positive airway pressure (nCPAP) circuitry.A prospective cohort study.University hospital sleep-disorders center.Eighty-two consecutive patients with obstructive sleep apnea syndrome were followed up for a median of 347 days (range, 3 to 530 days) after the initiation of nCPAP therapy.In 46 patients (56%), the occurrence of upper-airway symptoms led to the addition of a cold humidifier after a median time of 39 days (range, 2 to 94 days). In 23 of the 46 patients, the persistence of the symptoms indicated the secondary use of a heated humidifier after a median time of 28 days (range, 5 to 70 days). nCPAP use (mean +/- SD) was not influenced by cold humidification (4.58 +/- 2.05 h/d vs 4.7 +/- 2.48 h/d; p = 0.75), but it increased significantly with heated humidification (5.38 +/- 2.26 h/d vs 3.51 +/- 2.53 h/d; p0.01). Anthropometric characteristics, drying medications, clinical findings such as deformity of the nasal septum, symptoms of a chronic mucosa disease (CMD), a previous uvulopalatopharyngoplasty (UPPP), and polysomnographic parameters had no significant effect on the need for a cold humidifier. Age60 years (odds ratio [OR], 5.58; 95% confidence interval [CI], 1.69 to 18.43), drying medications (OR, 6.59; 95% CI, 1.29 to 33.51), presence of CMD (OR, 4.11; 95% CI, 1.24 to 13.58), and previous UPPP (OR, 4.56; 95% CI, 1.18 to 17.6) were found as significant risk factors for the addition of a heated humidifier.Our results demonstrate that heated humidification significantly improves the nCPAP daily rate of use and that its need may be predicted. |
| Databáze: | OpenAIRE |
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