Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp3-rich chemical space

Autor: Loïc Herter, Ilias Koutsopetras, Lorenzo Turelli, Thomas Fessard, Christophe Salomé
Rok vydání: 2022
Předmět:
Zdroj: Organic & Biomolecular Chemistry
ISSN: 1477-0539
1477-0520
DOI: 10.1039/d2ob01669a
Popis: Here, we disclose an efficient and modular approach toward new 1,2-disubstituted bicyclo[2.1.1]hexane modules via [2 + 2] cycloaddition. The system can readily be derivatized with numerous transformations, opening the gate to sp3-rich new chemical space.
Databáze: OpenAIRE