Outcomes of COVID-19 in Patients with Cirrhosis or Liver Transplantation

Autor:	Narendra S. Choudhary, Neeraj Saraf, Swapnil Dhampalwar, Arvinder S. Soin
Rok vydání:	2021
Předmět:	NAFLD non-alcoholic fatty liver disease medicine.medical_specialty ACLF acute-on chronic liver failure Cirrhosis Coronavirus disease 2019 (COVID-19) liver diseases ALT alanine transaminase NASH non-alcoholic steatohepatitis medicine.medical_treatment LFT liver function tests Review Article AST aspartate aminotransferase Liver transplantation LT liver transplantation Chronic liver disease SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Gastroenterology MELD model for end-stage liver disease 03 medical and health sciences 0302 clinical medicine HCWs health care workers Internal medicine medicine Risk of mortality ALI acute liver injury In patient COVID-19 Coronavirus disease 2019 immunosuppression Hepatology SARS-CoV-2 business.industry NASH ACE angiotensin converting enzyme related carboxypeptidase receptors Immunosuppression medicine.disease Decompensated cirrhosis mortality HR hazard ratio 030220 oncology & carcinogenesis CLD chronic liver disease 030211 gastroenterology & hepatology business OR Odds ratio
Zdroj:	Journal of Clinical and Experimental Hepatology
ISSN:	0973-6883
Popis:	Coronavirus disease 2019 (COVID-19) is associated with a significant morbidity and mortality in patients with cirrhosis. There is a significantly higher morbidity and mortality due to COVID-19 in patients with decompensated cirrhosis as compared to compensated cirrhosis, and in patients with cirrhosis as compared to non-cirrhotic chronic liver disease. The fear of COVID-19 before or after liver transplantation has lead to a significant reduction in liver transplantation numbers, and patients with decompensated cirrhosis remain at risk of wait list mortality. The studies in liver transplantation recipients show that risk of mortality due to COVID-19 is generally driven by higher age and comorbidities. The current review discusses available literature regarding outcomes of COVID-19 in patients with cirrhosis and outcomes in liver transplant recipients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3c248e064d1e6f7878934db19f6d0f https://doi.org/10.1016/j.jceh.2021.05.003 Zobrazit plný text záznamu Full Text from ScienceDirect