Long-term use of {mTORC}1 inhibitors in tuberous sclerosis complex associated neurological aspects

Autor:	Romina Moavero, Paolo Curatolo
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	long-term outcome congenital hereditary and neonatal diseases and abnormalities mTORC1 inhibitors mTORC1 03 medical and health sciences Tuberous sclerosis Epilepsy 0302 clinical medicine medicine Pharmacology (medical) Pharmacology Toxicology and Pharmaceutics (miscellaneous) PI3K/AKT/mTOR pathway Everolimus Subependymal giant cell astrocytoma business.industry rapamycin Health Policy tuberous Sclerosis complex subependymal giant cell astrocytoma food and beverages Autosomal dominant trait medicine.disease everolimus Settore MED/39 medicine.anatomical_structure 030220 oncology & carcinogenesis Cancer research mTOR TSC1 business 030217 neurology & neurosurgery medicine.drug
Popis:	Tuberous Sclerosis Complex (TSC) is an autosomal dominant disease caused by mutation in TSC1/2 genes, leading to the hyperactivation of the mammalian/mechanistic target of Rapamycin complex 1 (mTOR...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3bf0e57dceb022433c83497153c9b7 http://hdl.handle.net/2108/294264 Zobrazit plný text záznamu