Racial Differences in Risk Factors for Kidney Stone Formation
| Autor: | Andrew J. Cohen, Fredric L. Coe, Elaine M. Worcester, Christopher B. Riedinger, Anna L. Zisman |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Gerontology Epidemiology Urology MEDLINE Urine Critical Care and Intensive Care Medicine Risk Assessment White People Excretion Kidney Calculi chemistry.chemical_compound Risk Factors medicine Humans Aged Retrospective Studies Chicago Transplantation business.industry Incidence (epidemiology) Retrospective cohort study Original Articles Health Status Disparities Middle Aged Water-Electrolyte Balance medicine.disease Race Factors Black or African American Renal Elimination Urodynamics Treatment Outcome chemistry Nephrology Kidney stone disease Uric acid Calcium Female Kidney stones Racial differences business Biomarkers Demography |
| Zdroj: | Clin J Am Soc Nephrol |
| ISSN: | 1555-905X 1555-9041 |
| DOI: | 10.2215/cjn.12671019 |
| Popis: | BACKGROUND AND OBJECTIVES: Incidence of kidney stone disease is rising. It is not known whether mechanisms of stone formation differ across racial groups. Our objective was to identify differing lithogenic risk factors across racial groups in idiopathic nephrolithiasis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a retrospective cohort study evaluating metabolic risk factors in black and age-matched white idiopathic stone formers at our tertiary referral center. We compared serum and urine metabolic risk factors pre- and post-treatment across racial groups using analysis of covariance. Generalized linear modeling was used to build regression models for risk of stone formation in both groups. RESULTS: Among 117 black and 172 white stone formers, urine volume was lower in black stone formers (1.4±0.8 versus 2.0±0.8 L/d, P |
| Databáze: | OpenAIRE |
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