Enlargement of the membanous ventricular septum: An internal stigma of Down's syndrome
| Autor: | Glenn C. Rosenquist, Lauren J. Sweeney, Jon Amsel, Hugh A. McAllister |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Heart Defects
Congenital medicine.medical_specialty Down syndrome S syndrome Heart disease business.industry Cardiomegaly medicine.disease Stigma (anatomy) Surgery Heart disorder Maldevelopment Internal medicine Pediatrics Perinatology and Child Health Heart Septum cardiovascular system medicine Cardiology Humans Autopsy cardiovascular diseases Down Syndrome business Normal heart |
| Zdroj: | The Journal of Pediatrics. 85:490-493 |
| ISSN: | 0022-3476 |
| Popis: | A study of heart specimens without ventricular septal defect from patients with down's syndrome showed a significant enlargement of the membranous ventricular septum as compared to the normal heart. This increase in area of the ventricular septum occupied by membranous tissue from 2 to 9% may not only predispose patients with Down's syndrome to congenital heart disease, but may be one end of a spectrum of cardiac anomalies related to malalignment or maldevelopment of the ventricular septum in Down's syndrome. |
| Databáze: | OpenAIRE |
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